Nature Protocols article

High-fidelity probing of the structure and heterogeneity of extracellular vesicles by resonance-enhanced atomic force microscopy infrared spectroscopy

https://www.nature.com/articles/s41596-018-0109-3?WT.feed_name=subjects_materials-science

A new article from previous work by Dr Sally Kim et al as been published in Nature protocols this month detailing development of an atomic force microscope IR spectroscopy approach to probing the structural composition of single extracellular vesicles with nanoscale resolution. 

British Thoracic Society Winter Meeting 2018


British Thoracic Society


The 2018 Winter Meeting was held between 5-7th December at the Queen Elizabeth II Centre, London.


Dr. Charlotte Dean gave her talk entitled “Real-time imaging reveals novel insights into alveologenesis” at the plenary scientific symposium on the 6th December 2018. Charlotte presented recent findings which enlighten our understanding of the process of alveologenesis.

Recent workshop on Precision-Cut Lung Slices

A successful and fruitful workshop on the uses of precision-cut lung slices on 5th September was held at Imperial College London.  Organised by Dr Charlotte Dean and Dr Mark Griffiths, the workshop bought together a distinguished line-up of scientists and clinicians to discuss the cutting-edge applications of PCLS.

Programme:

10.00 Registration and Coffee

10.15 Welcome and introduction – Dr Charlotte Dean/ Dr Mark Griffiths

10.30 Dr Darcy Wagner (Lund University) ‘Using human precision cut lung slices to evaluate existing and novel therapeutics in chronic lung disease’

10.55 Dr James Harker (Imperial College London) ‘Lung resident germinal centres and their role in allergic asthma’

11.20-11.50 Coffee break

11.50 Dr Coralie Martin (Paris Natural History Museum) ‘Lung inflammation in chronic filariasis’

12.15 Dr Franz Puttur (Imperial College London) ‘Lung environmental guidance cues propel in vivo dynamic movement of group 2 innate lymphoid cells after inflammation’

12.45-2.00 Working lunch with 5 min presentations showcasing use of lung slices

2.00 Dr John-Poul Ng-Blichfeldt (MRC, LMB) ‘Using adult lung organoids to investigate regeneration’

2.25 Dr Leo Carlin (Beatson Institute) ‘Using PCLS to probe the regulation of immune cells in cancer’

2.50 Dr Charlotte Dean (Imperial College London) ‘Novel insights into alveologenesis using real-time imaging of PCLS’

3.15 Free Discussion and wrap up with refreshments

4.00 Close

A-level student visit- 10 July 2018

The Dean lab is hosting a visit from 3 A-level students as part of the successful National Heart and Lung Institute Outreach programme. Students spent the afternoon with PhD students, postdocs and lab heads talking about their research. 34 students from different local schools took part in the work experience internships and rotated through four different areas of NHLI to gain insight into a variety of topics.  At the end of the week the students had the opportunity to give an oral/poster presentation to their peers on their favourite topic.

To find out more about this NHLI outreach program contact:

Dr. Mohamed Shamji